Best Bed Bug Killer

By Katie Dyal

Bed bugs are one of the biggest hassles that you can experience in your home. If you find yourself in an infestation situation but can’t afford or want to avoid hiring pest control professionals, there are other options out there. Choose a bed bug killer that suits your needs as you brave your bedroom battlefield yourself. 

From powders to sprays to fun applicators and beyond, these products make the venture of debugging less daunting and more doable. In addition, ingredients used can widely vary from product to product. Keep reading to learn more about our top picks for best bed bug killers and what to look for when shopping for your own. 

Our Picks for the Best Bed Bug Killer

By clicking on the product links in this article, Mattress Advisor may receive a commission fee at no cost to you, the reader. Read full disclosure statement.
Safer Brand

Best Budget

Safer Brand

Safer Brand’s Diatomaceous Earth Insect Killer is an organic product that eliminates insects without the use of harsh chemicals. 

The application process is quick and easy. Simply sprinkle this mix of fossilized fresh-water algae to kill the bugs and keep them away. Safe for use in both indoor and outdoor settings, this powder can be used anywhere that bed bugs might linger, including furniture. Allow up to 48 hours of time to elapse in order to start seeing your pest problem dissipate.

HARRIS Bed Bug Killer

Best Luxury


The Harris Bed Bug Killer Liquid Spray is a residual treatment that kills quickly and protects your space for up to 16 weeks. 

This formula was made to target bugs that have built up a resistance to traditional pesticides, making your unwanted  “pyrethroid-resistant” visitors evacuate in no time. Use as a spot treatment in hard-to-reach nooks and crannies or spray directly. This product is meant to cover all bases and is EPA registered and approved for use indoors. Its odorless nature is surprising due to its level of powerful strength.


Most Eco-Friendly


The EcoRaider Bed Bug Killer is a great choice if you’re looking for an effective solution of the utmost safety for you and your family. 

This botanical-based spray is completely non-toxic, making it sensitive enough to be called pet-friendly, child-friendly, and safe on skin. Because of the gentleness of this formula, this option can be sprayed directly onto mattresses to stop bed bug infestations from spreading. Don’t underestimate the power of this green product; it has been proven by the USDA IR-4 Public Health Pesticide Program for being especially powerful in eradicating infections. This bed bug killer promises to start working within one hour of the first use.

Home Defense Max Bed Bug, Flea and Tick Killer by Ortho

Easiest To Use


The Home Defense Max Bed Bug, Flea and Tick Killer by Ortho contains a tough formula that means business. 

Proven to destroy all bed bugs in its path, this spray also knocks out any eggs that these pesky intruders may leave behind. The best part of this option may just be its applicator. An included battery-operated wand helps your aim with great precision and advanced technology. Its flexibility allows you to get into the hard-to-reach places that bed bugs can but you can’t. It applies evenly and consistently every time without leaving behind stains or harsh odors. It’s- dare we say- fun to use? Weighing in at 1.5 gallons, this option by Ortho is also a great value for the price.

What to Look For in Your Next Bed Bug Killer

Eliminating bed bugs on your own is no small feat. When choosing a product that can stand up to the test, it is imperative to read all labels carefully. Review the importance of application, ingredients used, and length of effect, and you’ll see how these factors directly influence each other and the outcome of your bed bug battle.

  • Application: A problem of bed bugs can be solved in many different ways through a range of different products. Choosing between a spray, powder, or gel depends on the severity of your problem, where your problem is located, and the ingredients you feel most comfortable with.
  • Ingredients Used: Is being eco-friendly a priority for you? Organic, all-natural products are surprisingly just as effective and quick to work as their more chemical-driven competitors. Watch your pets and children around the stronger stuff; more chemicals mean more long-lasting, but it can be dangerous for your family.
  • Length of Effect: This one works in tandem with the factor above. Harsher chemicals may not be as safe; however, they will give you peace of mind that you won’t be bugged again by these impervious pests.


We like to think we have your back when bed bugs attack. With the choice of one of these carefully reviewed products, you’ll be saying goodbye to bites in no time. You can start to welcome your safe living space back in as little as one hour. With the help of our top picks for bed bug killers, you’ll have pest control under control. 

Comments (0)

Leave a Comment

Your email address will not be published. Required fields are marked *