Best Hypoallergenic Mattress Protectors

By Katie Dyal

When it comes to keeping your bedroom free of allergens, bacteria, and pests, it’s not hard to do your part. Hypoallergenic bedding such as pillows, sheets, and mattresses are an effortless way to practice preventative care. These materials stop problems before they start, which will keep you from losing time, money and sleep. 

Dealing with allergies, or even worse, an infestation doesn’t have to be your reality. With a hypoallergenic mattress protector, you can chill out and relax knowing that you’re safe from dirty intruders. Keep on reading to discover our top picks for the best hypoallergenic mattress protectors.

Our Top Picks for the Best Hypoallergenic Mattress Protectors

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Best Budget


The Premium Smooth Fabric Mattress Protector by Linenspa will have you sleeping in peace knowing that you’re safe. 

This option works wonderfully to keep allergies away while still providing a soft landing to rest on. Made with a polyurethane backing, it’s 100-percent waterproof material will protect from spills, stains and anything else worth repelling. This protector is ultra-thin, meaning that you’ll barely notice it’s there. It’s noiseless, breathable and odorless. This mattress protector comes in a fitted sheet style that effortlessly stretches over any queen-size mattress. It is fully elasticized and made with extra deep pockets, meaning that it will stay put on even the bulkiest of mattresses. This 60-inch by 80-inch option is easy to clean as well; simply put it through the washing machine and dry on low heat.

PlushDeluxe’s Premium Zippered Mattress Encasement

Best Luxury


PlushDeluxe’s Premium Zippered Mattress Encasement will provide an impressive fortress for your bed. 

With this product, you’ll get a good night’s sleep that’s cozy and worry-free. This option is our top pick for luxury due to its fit. It fully encases your mattress with a zipper closure and velcro flap, protecting every inch of your bed. With its tight and precise closure, there’s no way that allergens or bugs will bug you. The terry cotton material is backed by a 100-percent waterproof membrane, ensuring that your mattress is protected on all six sides. You can also be sure that the material itself is harmless. This material is free from vinyl, PVC and phthalates. The all-encompassing mattress encasement is a 76-inch by 80-inch size and can accommodate mattress depths from 12 inches to 15 inches.


Best Value


The Queen Size Premium Hypoallergenic Waterproof Mattress Protector by SafeRest allows you to snooze without sneezing. 

This mattress protector is fantastic at warding off allergens, but that’s not the only benefit it provides. Its cotton terry surface is super-soft to the touch, and backed with a membrane coating that’s waterproof and noiseless. This material also offers a level of breathability that allows you to rest safely and comfortably. SafeRest’s mattress protector comes in a fitted sheet style design, measuring in at 60 inches by 80 inches. Its 18-inch pockets are deep enough to fit even the tallest mattresses. Once you put it on, it will stay put until it’s time for a refresh. To clean, simply pop it in the washing machine and tumble dry on low. This mattress protector is easy to care for, easy to put on and will help you sleep with ease.


Also Great


ZAMAT’s 100-Percent Waterproof Mattress Protector will protect you and your bed from whatever life throws at you. 

This option focuses on fighting bacteria so you can focus on getting your beauty sleep. This protector stretches over your mattress to create a soft terry cloth and polyester surface that’s also 100-percent waterproof. This protector is very breathable and will wick away moisture to keep your mattress clean and dry. ZMAT has your mattress covered with the deep fit of this fitted sheet style mattress protector. Simply stretch on and snooze away for a night of effortlessly healthy sleep. The elastic of this option is more tight-fitting than most, meaning it will stay put just as well as its zippered counterparts. When it’s time for a change, this hassle-free protector is completely machine-washable.

What to Look For in Your Next Hypoallergenic Mattress Protector

When looking for a hypoallergenic mattress protector, you may not know where to look first. How can you be sure which are really ready for the job? There are a couple of key things to note when shopping for covers of this kind. Material, size, and closure will give you closure on the one that’s right for you.

Material: Material will tell you a lot about a mattress protector. Matters of durability, breathability, and comfort all are included in this one factor. Once you’ve found one that meets your standards in those categories, make sure that it’s also 100-percent waterproof. A waterproof coating will really seal the deal on how protective a protector really is. 

Size: A mattress protector won’t be able to do its job well if it’s not compatible with your mattress. Make sure you pay attention to measurements, especially with zippered options. 

Closure: Hypoallergenic mattress protectors come in different styles of fit. This choice will come down to just how much coverage you’ll need to sleep easy.


As you can see, hypoallergenic materials really can make a world of difference in the invisible environment of your bed set-up. What seems to be a clean area can sometimes be deceiving; allergens, dust mites, bacteria and bed bugs are undetectable until it’s too late. You can be diligent about washing your sheets and keeping this space tidy, but this fact remains; you can’t put your mattress through the washing machine. With a hypoallergenic mattress protector, you can put all of these worries to rest. 

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